Anti-HDAC4 (phospho Ser632) Antibody (A283630)

Anti-HDAC4 (phospho Ser632) Antibody

Rabbit polyclonal antibody to HDAC4 (phospho Ser632).

This antibody recognises Histone deacetylase 4, also known as HDAC4, when phosphorylated at serine 632. Histone deacetylases are chromatin-modifying enzymes that are involved in the regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. Histone deacetylase 4 is a class II histone deacetylase, which shuttles back and forth between nucleus and cytoplasm.Histone deacetylase 4 is phosphorylated at serine 632 by calcium/calmodulin-dependent protein kinase (CaMK).

WB: 1:500 - 1:2,000

Human, Mouse, Rat

Phospho-specific peptide corresponding to residues surrounding Ser632 of human histone deacetylase 4.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Histone deacetylase 4 (pSer632) antibody recognizes histone deacetylase 4, also known as HDAC4, when phosphorylated at serine 632. Histone deacetylases are chromatin-modifying enzymes that are involved in the regulation of many aspects of cell biology including tissue differentiation, autophagy, apoptosis, migration, mitosis and angiogenesis. Histone deacetylase 4 is a class II histone deacetylase, which shuttles back and forth between nucleus and cytoplasm.Histone deacetylase 4 is phosphorylated at serine 632 by calcium/calmodulin-dependent protein kinase (CaMK) (Wang et al. 2014).

HD4, Histone deacetylase 4, KIAA0288