Recombinant mouse monoclonal [rFABP3/8534] antibody to H-FABP.
Specificity
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.
Applications
IHC-P
Positive Control
Human heart or skeletal muscle.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Human recombinant FABP3 protein fragment (around Amino Acids 1-127). The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
rFABP3/8534
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
15 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.