Anti-GRP94 Antibody [SPM249] (A250210)

Anti-GRP94 Antibody [SPM249]

Rat monoclonal [SPM249] antibody to GRP94.

This antibody recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Flow Cytometry, IF, WB, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Monkey, Horse, Bovine, Sheep, Pig, Rabbit, Canine, Rat, Mouse, Hamster, Guinea Pig, Chicken, Xenopus laevis

Native Glucose Regulated Protein 94 purified from chicken oviducts.

Rat

Monoclonal

SPM249

IgG2a

kappa

Protein A/G chromatography.

200 µg/ml

94 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-GRP94 Antibody [SPM249] - BSA and Azide free (A253390).

94 kDa glucose-regulated protein, Endoplasmin, gp96 homolog, GRP-94, Heat shock protein 90 kDa beta member 1, Heat shock protein family C member 4, HSP90B1, HSPC4, TRA1, Tumor rejection antigen 1