Anti-Growth Hormone Antibody [rGH/4887] - BSA and Azide free
Description
Recombinant mouse monoclonal [rGH/4887] antibody to Growth Hormone.
Specificity
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human Growth Hormone.
Host
Mouse
Clonality
Monoclonal
Clone ID
rGH/4887
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
20 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Negative Tissue Control: Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain using Anti-Growth Hormone Antibody [rGH/4887] at 2µg/ml in PBS for 30 minutes at room temperature.
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