Recombinant Anti-Growth Hormone Antibody [GH/4886R] (A277991)

Anti-Growth Hormone Antibody [GH/4886R]

Recombinant rabbit monoclonal [GH/4886R] antibody to Growth Hormone.

Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human Growth Hormone.

Rabbit

Monoclonal

GH/4886R

IgG

Protein A/G chromatography.

200 µg/ml

20 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Growth Hormone Antibody [GH/4886R] - BSA and Azide free (A278579).

GH, GH-N, GH1, Growth hormone 1, Pituitary growth hormone, Somatotropin