Anti-Granzyme B Antibody [GB10] (Biotin) (A280503)

Anti-Granzyme B Antibody [GB10] (Biotin)

Mouse monoclonal [GB10] antibody to Granzyme B (Biotin).

This antibody recognises the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs).Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.

ELISA: 1 µg/ml

Human, Chimpanzee, Monkey, Rhesus Monkey

Purified human Granzyme B.

Mouse

Monoclonal

GB10

IgG1

Protein A affinity chromatography of tissue culture supernatant.

500 µg/ml

Liquid

Supplied in TRIS Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human granzyme B antibody, clone GB10 recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs).Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.

C11, Cathepsin G-like 1, CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, GZMB, Lymphocyte protease

This product is for research use only. It is not intended for diagnostic or therapeutic use.