Anti-Glucose Transporter GLUT1 Antibody [GLUT1/7308] - BSA and Azide free (A316409)

Anti-Glucose Transporter GLUT1 Antibody [GLUT1/7308] - BSA and Azide free

Mouse monoclonal [GLUT1/7308] antibody to Glucose Transporter GLUT1.

Recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).

K562, A431, MDA-MB-231 cells or erythrocytes. Mesothelioma or breast, colon and ovarian carcinoma.

IHC: 1-2 µg/ml

Human

Recombinant fragment of human GLUT1 protein (around Amino Acids 200-400). The exact sequence is proprietary.

Mouse

Monoclonal

IgG

Protein A/G chromatography.

1 mg/ml

55 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, Solute carrier family 2, facilitated glucose transporter member 1