This antibody recognises glucagon, a pancreatic hormone whose actions are antagonistic to insulin, functioning to increase blood glucose through stimulation of glycogenolysis and gluconeogenesis in the liver. Glucagon is a ligand for the glucagon receptor, a G-protein linked receptor whose signalling pathway controls cell proliferation.Glucagon is secreted from A-cells within the Islets of Langerhans in the pancreas.
Applications
ELISA
Dilutions
ELISA: 1:200 - 1:20,000
Reactivity
Human
Immunogen
Synthetic peptide corresponding to amino acids 8-18 of human glucagon.
Sequence
AGLFVMLVQGS
Host
Goat
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Purification
Protein G affinity chromatography.
Concentration
5 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Goat anti Human glucagon antibody detects glucagon, a pancreatic hormone whose actions are antagonistic to insulin, functioning to increase blood glucose through stimulation of glycogenolysis and gluconeogenesis in the liver. Glucagon is a ligand for the glucagon receptor, a G-protein linked receptor whose signalling pathway controls cell proliferation.Glucagon is secreted from A-cells within the Islets of Langerhans in the pancreas.