Anti-GAD65 Antibody [GAD2/6484] (A314985)

Anti-GAD65 Antibody [GAD2/6484]

Mouse monoclonal [GAD2/6484] antibody to GAD65.

This MAb recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD s) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (

ELISA, WB, IHC-P

Human pancreas or brain.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment of human GAD2 (GAD65) protein (around Amino Acids 1-200). The exact sequence is proprietary.

Mouse

Monoclonal

GAD2/6484

IgG2b

Protein A/G chromatography.

200 µg/ml

65 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

65 kDa glutamic acid decarboxylase, GAD-65, GAD2, Glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform