Anti-FLT3 Antibody [FLT3/2458] (A248574)

Anti-FLT3 Antibody [FLT3/2458]

Mouse monoclonal [FLT3/2458] antibody to FLT3.

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human FLT3 protein.

Mouse

Monoclonal

FLT3/2458

IgG2b

Protein A/G chromatography.

200 µg/ml

160 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-FLT3 Antibody [FLT3/2458] - BSA and Azide free (A251756).

CD135, Fetal liver kinase-2, FL cytokine receptor, FLK-2, FLK2, FLT-3, Fms-like tyrosine kinase 3, Receptor-type tyrosine-protein kinase FLT3, Stem cell tyrosine kinase 1, STK-1, STK1