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Recombinant Anti-Filaggrin Antibody [FLG/3909R] (A277984)

Recombinant rabbit monoclonal [FLG/3909R] antibody to Filaggrin for WB.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-Filaggrin Antibody [FLG/3909R]
Description
Recombinant rabbit monoclonal [FLG/3909R] antibody to Filaggrin.
Specificity
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Applications
WB
Dilutions
WB: 2-4 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 198-288, of human Filaggrin. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
FLG/3909R
Isotype
IgG
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
26-45 kDa (Processed) / 350 kDa (Profilaggrin)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Filaggrin Antibody [FLG/3909R] - BSA and Azide free (A278572).
Synonyms
FLG
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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