This antibody recognises FADD, also known as Fas-associated death domain protein, MORT1, growth-inhibiting gene 3 protein or mediator of receptor induced toxicity. FADD is a 23 kDa protein consisting of a C-terminal death domain and an N-terminal death effector domain. FADD is involved in forming the death-inducing signalling complex (DISC) during apoptosis.
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:200, WB: 1:500 - 1:2,000
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human FADD.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Molecular Weight
Approximately 25 kDa in cell lysates and tissue lysates under reducing conditions
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti FADD antibody recognizes FADD, also known as Fas-associated death domain protein, MORT1, growth-inhibiting gene 3 protein or mediator of receptor induced toxicity. FADD is a 23 kDa protein consisting of a C-terminal death domain and an N-terminal death effector domain. FADD is involved in forming the death-inducing signalling complex (DISC) during apoptosis.
Synonyms
FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, MORT1