Rabbit polyclonal antibody to Ezrin (phospho Thr567).
Specificity
This antibody recognises ezrin, also known as villin-2, when phosphorylated at threonine 567. Ezrin is a member of the Ezrin Radixin Moesin (ERM) family. Ezrin functions as a linker molecule between the plasma membrane and the cytoskeleton. Phosphorylation of ezrin at threonine 567 regulates binding to F-actin and the cell membrane.
Applications
WB
Dilutions
WB: 1:500 - 1:2,000
Reactivity
Human, Mouse, Rat
Immunogen
Phospho-specific peptide corresponding to residues surrounding Thr567 of human ezrin.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti ezrin (pThr567) antibody recognizes ezrin, also known as villin-2, when phosphorylated at threonine 567. Ezrin is a member of the Ezrin Radixin Moesin (ERM) family. Ezrin functions as a linker molecule between the plasma membrane and the cytoskeleton. Phosphorylation of ezrin at threonine 567 regulates binding to F-actin and the cell membrane (Zhu et al. 2007).