Anti-Estrogen Receptor alpha Antibody [AER311] (A314933)

Anti-Estrogen Receptor alpha Antibody [AER311]

Mouse monoclonal [AER311] antibody to Estrogen Receptor alpha.

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa495-595 of E/F domain. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Flow Cytometry, IF

MCF-7 Cells or Breast Carcinomas

Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml

Human, Bovine, Porcine, Mouse, Rat

ER purified from cow uterus.

Mouse

Monoclonal

AER311

IgG2a

Protein A/G chromatography.

200 µg/ml

~67 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ER, ER-alpha, ESR, ESR1, Estradiol receptor, Estrogen receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1