Mouse monoclonal [1D5] antibody to Estrogen Receptor alpha.
Specificity
This antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
Applications
IHC-P
Dilutions
IHC-P: 1:100-1:200
Reactivity
Human
Immunogen
Recombinant human Estrogen Receptor alpha protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
1D5
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Molecular Weight
~67 kDa
Purity
Tissue culture supernatant.
Product Form
Liquid
Formulation
Supplied as an aliquot of tissue culture supernatant with 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
ER, ER-alpha, ESR, ESR1, Estradiol receptor, Estrogen receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1
![Immunohistochemistry - Anti-Estrogen Receptor alpha Antibody [1D5] (A254219) - Antibodies.com](https://cdn.antibodies.com/image/catalog/254/A254278_1.jpg?profile=product_top)
![Immunohistochemistry - Anti-Estrogen Receptor alpha Antibody [1D5] (A254219) - Antibodies.com](https://cdn.antibodies.com/image/catalog/254/A254278_1.jpg?profile=product_top_thumb)
![Immunohistochemistry - Anti-Estrogen Receptor alpha Antibody [1D5] (A254219) - Antibodies.com](https://cdn.antibodies.com/image/catalog/254/A254278_1.jpg?profile=product_image)
![Western Blot - Anti-Estrogen Receptor alpha Antibody [ER506] - BSA and Azide free (A251663) - Antibodies.com](https://cdn.antibodies.com/image/catalog/251/A251663_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Estrogen Receptor alpha Antibody [ESR1/3557] (A248479) - Antibodies.com](https://cdn.antibodies.com/image/catalog/248/A248479_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Estrogen Receptor alpha Antibody [ESR1/3557] - BSA and Azide free (A251661) - Antibodies.com](https://cdn.antibodies.com/image/catalog/251/A251661_1.jpg?profile=product_alternative)
![Western Blot - Anti-Estrogen Receptor alpha Antibody [ER506] (A248481) - Antibodies.com](https://cdn.antibodies.com/image/catalog/248/A248481_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Estrogen Receptor alpha Antibody [ESR1/1904] (A248471) - Antibodies.com](https://cdn.antibodies.com/image/catalog/248/A248471_1.jpg?profile=product_alternative)
![Immunohistochemistry - Anti-Estrogen Receptor alpha Antibody [ESR1/1904] - BSA and Azide free (A251653) - Antibodies.com](https://cdn.antibodies.com/image/catalog/251/A251653_1.jpg?profile=product_alternative)
