Anti-EMR2 Antibody [2A1] (A279157)

$480

Mouse monoclonal [2A1] antibody to EMR2 for WB, IP, Flow Cytometry and IHC-Fr.

Alternative Formats and ConjugatesAlternative Formats

PE

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 4-6 business days.
Name
Anti-EMR2 Antibody [2A1]
Description
Mouse monoclonal [2A1] antibody to EMR2.
Specificity
This antibody recognises human EMR2, a member of the epidermal growth factor-seven transmembrane (EGF-TM7) family of proteins, which is closely related to CD97. EMR2, also known as CD312, is predominantly expressed on myeloid dendritic cells, monocytes and tissue macrophages. Various isoforms of EMR2 have been documented. The ligand for the largest isoform of EMR2 has recently been identified as chrondroitin sulphate, which binds to the fourth EGF-like module of EMR2. recognises the stalk region of EMR2.
Applications
WB, IP, Flow Cytometry, IHC-Fr
Dilutions
Flow Cytometry: 1:50 - 1:200, IHC-Fr: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 106 cells in 100µl.
Reactivity
Human
Immunogen
NIH/3T3 cells stably transfected with EMR2 (EGF1-5) cDNA.
Host
Mouse
Clonality
Monoclonal
Clone ID
2A1
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human CD312 antibody, clone 2A1 recognizes human EMR2, a member of the epidermal growth factor-seven transmembrane (EGF-TM7) family of proteins, which is closely related to CD97. EMR2, also known as CD312, is predominantly expressed on myeloid dendritic cells, monocytes and tissue macrophages. Various isoforms of EMR2 have been documented. The ligand for the largest isoform of EMR2 has recently been identified as chrondroitin sulphate, which binds to the fourth EGF-like module of EMR2. Mouse anti Human CD312 antibody, clone 2A1 recognizes the stalk region of EMR2.
Synonyms
ADGRE2, Adhesion G protein-coupled receptor E2, CD312, EGF-like module receptor 2, EGF-like module-containing mucin-like hormone receptor-like 2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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