Anti-DR6 Antibody (A283887)

Anti-DR6 Antibody

Rabbit polyclonal antibody to DR6.

This antibody recognises human Tumor necrosis factor receptor superfamily member 21, also known as death domain containing receptor DR6, Death receptor 6 or CD358. DR6 is a 655 amino acid ~72 kDa type 1 single pass transmembrane glycoprotein with four extracellular cysteine rich repeats and a single cytoplasmic death domain. DR6 is widely expressed in human tissues and cell lines. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK.

WB: 1:500

Human

A peptide corresponding to amino acids 42-56 of human DR6 precursor.

QPEQKASNLIGTYRH

Rabbit

Polyclonal

IgG

500 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human DR6 antibody recognizes human Tumor necrosis factor receptor superfamily member 21, also known as death domain containing receptor DR6, Death receptor 6 or CD358. DR6 is a 655 amino acid ~72 kDa type 1 single pass transmembrane glycoprotein with four extracellular cysteine rich repeats and a single cytoplasmic death domain. DR6 is widely expressed in human tissues and cell lines. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK (Pan et al. 1998).

CD358, Death receptor 6, TNFRSF21, Tumor necrosis factor receptor superfamily member 21