Anti-DPP4 Antibody [H207-1082] (PE) (A280546)

Anti-DPP4 Antibody [H207-1082] (PE)

Rat monoclonal [H207-1082] antibody to DPP4 (PE).

This antibody recognises mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma.The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl. The Fc region of monoclonal antibodies may bind to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/BUF041B).

Mouse

Rat

Monoclonal

H207-1082

IgG2a

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water.

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Rat anti Mouse CD26 antibody, clone H207-1082 recognizes mouse CD26, which is also known as thymocyte-activating molecule (THAM). Murine CD26 is a type II integral membrane dipeptidyl-peptidase that is expressed at the cell surface as a heterodimer, of approximately 220 kDa, and has a soluble form in the plasma.The CD26 molecule is a multifunctional glycoprotein that has ectopeptidase activity and is also reported to be involved in cell adhesion, signal transduction in T lymphocytes and HIV infection. CD26 is differentially expressed on developing thymocytes and is upregulated on activated T-cells but is not expressed on resting and thioglycollate stimulated macrophages. Expression of CD26 has also been reported on cells from a variety of non-haematopoietic tissues including liver, intestine and kidney.

ADABP, ADCP-2, ADCP2, Adenosine deaminase complexing protein 2, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CD206, CLEC13D, CLEC13DL, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, hMR, Human mannose receptor, Macrophage mannose receptor 1, Macrophage mannose receptor 1-like protein 1, MMR, MRC1, MRC1L1, T-cell activation antigen CD26, TP103

This product is for research use only. It is not intended for diagnostic or therapeutic use.