Anti-DPP4 Antibody [DPP4/7415] (A314895)

Anti-DPP4 Antibody [DPP4/7415]

Mouse monoclonal [DPP4/7415] antibody to DPP4.

Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

WB, IHC-P

Human lymph nodes or tonsil.

WB: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human DPP4 protein. The exact sequence is proprietary.

Mouse

Monoclonal

DPP4/7415

kappa

Protein A/G chromatography.

200 µg/ml

110 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ADABP, ADCP-2, ADCP2, Adenosine deaminase complexing protein 2, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CD206, CLEC13D, CLEC13DL, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, hMR, Human mannose receptor, Macrophage mannose receptor 1, Macrophage mannose receptor 1-like protein 1, MMR, MRC1, MRC1L1, T-cell activation antigen CD26, TP103