Anti-Desmoglein 3 Antibody [5H10] - BSA and Azide free (A251556)

Anti-Desmoglein 3 Antibody [5H10] - BSA and Azide free

Mouse monoclonal [5H10] antibody to Desmoglein 3.

This antibody recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.

Flow Cytometry, IF, WB

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml

Human

Recombinant fragment of extracellular human DSG3 protein.

Mouse

Monoclonal

5H10

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

130 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Desmoglein 3 Antibody [5H10] (A248374).

130 kDa pemphigus vulgaris antigen, Cadherin family member 6, CDHF6, Desmoglein-3, DSG3, PVA