This antibody binds glandular epithelial cells (endocrine and exocrine) as well as mesothelial cells and epithelia of the digestive, respiratory and urogenital tract. Most adenocarcinomas derived from these cells are positive. The M20 epitope has been mapped to amino acids 353-367 on the alpha helical rod domain of Cytokeratin 8.
Applications
Flow Cytometry, ICC, IHC-Fr, IHC-P, WB
Reactivity
Human, Rabbit, Rat
Immunogen
Keratin isolated from the Human breast carcinoma cell line MCF-7.
Host
Mouse
Clonality
Monoclonal
Clone ID
M20
Isotype
IgG1
Conjugate
Unconjugated
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
Synonyms
CK-8, CYK8, Cytokeratin-8, K8, Keratin, type II cytoskeletal 8, Keratin-8, KRT8, Type-II keratin Kb8