Recombinant Anti-Cytokeratin 7 Antibody [rKRT7/8763] (A314874)

Anti-Cytokeratin 7 Antibody [rKRT7/8763]

Recombinant mouse monoclonal [rKRT7/8763] antibody to Cytokeratin 7.

It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract.This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).

Carcinoma of ovary, lung, cervix, or breast

IHC: 1-2 µg/ml

Human

Recombinant full-length human KRT7 protein.

Mouse

Monoclonal

rKRT7/8763

IgG2b

Protein A/G chromatography.

200 µg/ml

55 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CK-7, Cytokeratin-7, K7, Keratin, type II cytoskeletal 7, Keratin-7, KRT7, Sarcolectin, SCL, Type-II keratin Kb7