Anti-Cytokeratin 7 Antibody [KRT7/3733] - BSA and Azide free
Description
Mouse monoclonal [KRT7/3733] antibody to Cytokeratin 7.
Specificity
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. MAb to cytokeratin 7 is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Applications
WB, IHC-P
Positive Control
HeLa or SK-BR3 cells. Carcinoma of ovary, lung, cervix, or breast (IHC).
Dilutions
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human KRT7 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
KRT7/3733
Isotype
IgG1
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
55 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
CK-7, Cytokeratin-7, K7, Keratin, type II cytoskeletal 7, Keratin-7, KRT7, Sarcolectin, SCL, Type-II keratin Kb7
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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