Recombinant Anti-Cytokeratin 6A Antibody [rKRT6A/2100] - BSA and Azide free (A252311)

Anti-Cytokeratin 6A Antibody [rKRT6A/2100] - BSA and Azide free

Recombinant mouse monoclonal [rKRT6A/2100] antibody to Cytokeratin 6A.

This antibody recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas.

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human Cytokeratin 6A protein.

Mouse

Monoclonal

rKRT6A/2100

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

58 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Cytokeratin 6A Antibody [rKRT6A/2100] (A249131).

CK-6A, CK-6D, Cytokeratin-6A, Cytokeratin-6D, K6A, Keratin, type II cytoskeletal 6A, Keratin-6A, KRT6A, KRT6D, Type-II keratin Kb6