Anti-Cytokeratin 14 Antibody [KRT14/4130] - BSA and Azide free (A278271)

Anti-Cytokeratin 14 Antibody [KRT14/4130] - BSA and Azide free

Mouse monoclonal [KRT14/4130] antibody to Cytokeratin 14.

Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells.Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors.Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 351-472, of human Cytokeratin 14. The exact sequence is proprietary.

Mouse

Monoclonal

KRT14/4130

IgG2b

Protein A/G chromatography.

1 mg/ml

50 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Cytokeratin 14 Antibody [KRT14/4130] (A277683).

CK-14, Cytokeratin-14, K14, Keratin, type I cytoskeletal 14, Keratin-14, KRT14