Anti-Cystatin C Antibody [Cyst24] (A280190)

Anti-Cystatin C Antibody [Cyst24]

Mouse monoclonal [Cyst24] antibody to Cystatin C.

This antibody recognises human Cystatin C, a member of the type 2 cystatin superfamily. Cystatin C is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a ~13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells.Changes in cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that cystatin C can be used as a marker of renal failure.

Immunoassay, ELISA

Human

Mouse

Monoclonal

Cyst24

IgG1

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti human Cystatin C antibody, clone Cyst24 detects human Cystatin C, a member of the type 2 cystatin superfamily. Cystatin C is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a ~13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells.Changes in cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that cystatin C can be used as a marker of renal failure.

CST3, Cystatin-3, Cystatin-C, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin