This antibody recognises CD184, also known as C-X-C chemokine receptor type 4 (CXCR4), LESTR or SDF-1 receptor. CD184 is a member of the G-protein coupled receptor 1 family and a receptor for the chemokine SDF-1 (stromal cell-derived factor 1). CD184 also acts as a receptor for extracellular ubiquitin and as a coreceptor for HIV-1. CD184/CXCR4 is involved in multiple processes including chemotaxis, cell proliferation, survival and adhesion.
Applications
WB, IHC-P
Dilutions
IHC-P: 1:50 - 1:100, WB: 1:500 - 1:1,000
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human CXCR4.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Molecular Weight
Approximately 70 kDa in cell lysates and tissue lysates under reducing conditions
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti CD184/CXCR4 antibody recognizes CD184, also known as C-X-C chemokine receptor type 4 (CXCR4), LESTR or SDF-1 receptor. CD184 is a member of the G-protein coupled receptor 1 family and a receptor for the chemokine SDF-1 (stromal cell-derived factor 1). CD184 also acts as a receptor for extracellular ubiquitin and as a coreceptor for HIV-1. CD184/CXCR4 is involved in multiple processes including chemotaxis, cell proliferation, survival and adhesion.