Anti-CXCL2 Antibody - BSA and Azide free (A283920)

Anti-CXCL2 Antibody - BSA and Azide free

Rabbit polyclonal antibody to CXCL2.

This antibody recognises human GRO-beta, also known as Growth-regulated protein beta, C-X-C motif chemokine 2, Macrophage inflammatory protein 2-alpha, MIP-2a or CXCL2. GRO beta is a ~7.9 kDa CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils.Like GRO-alpha (CXCL1) and GRO-gamma (CXCL3), GRO-beta contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, GRO-beta has a lower potency and receptor binding affinity.

WB, ELISA, IHC-P, Functional Assays

ELISA: 0.5 µg/ml, Functional Assays: 0.5 - 1 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human GRO-beta.

Rabbit

Polyclonal

IgG

Lyophilized

Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human GRO beta antibody recognizes human GRO-beta, also known as Growth-regulated protein beta, C-X-C motif chemokine 2, Macrophage inflammatory protein 2-alpha, MIP-2a or CXCL2. GRO beta is a ~7.9 kDa CXC chemokine and one of three closely related, but distinct GRO gene products, which act as chemoattractants and activators of neutrophils and basophils.Like GRO-alpha (CXCL1) and GRO-gamma (CXCL3), GRO-beta contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors, GRO-beta has a lower potency and receptor binding affinity (Geiser et al. 1993).

C-X-C motif chemokine 2, Gro-beta, GRO2, GROB, Growth-regulated protein beta, Macrophage inflammatory protein 2-alpha, MIP2-alpha, MIP2A, SCYB2