Anti-Clusterin Antibody [CLU/4721] (A314796)

Anti-Clusterin Antibody [CLU/4721]

Mouse monoclonal [CLU/4721] antibody to Clusterin.

Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. Two subunits, -Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis.

Human pancreas, tonsil or cervix.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 150-300) of human CLU protein. The exact sequence is proprietary.

Mouse

Monoclonal

CLU/4721

kappa

Protein A/G chromatography.

200 µg/ml

70 kDa (precursor) / 36-39 kDa (alpha) / 34-36 kDa (beta)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Aging-associated gene 4 protein, Apo-J, APOJ, Apolipoprotein J, CLI, CLU, Complement cytolysis inhibitor, Complement-associated protein SP-40,40, Ku70-binding protein 1, KUB1