Anti-Chromogranin A Antibody (A282744)

Anti-Chromogranin A Antibody

Sheep polyclonal antibody to Chromogranin A.

This antibody recognises human chromogranin A, a secreted peptide that inhibits glucose-induced insulin release. Chromogranin A is an activator of microglia and is notably upregulated and prominantly expressed in the senile plaques associated with Alzheimer's disease.

IHC-P, ELISA

IHC-P 1: 1:25 - 1:100

Human, Bovine, Chimpanzee, Dog, Horse, Pig, Mouse, Rat

Synthetic peptide sequence LPVNSPMNKGDTEVM corresponding to amino acids 1 - 15 of the native molecule conjugated to Keyhole Limpet Haemocyanin.

LPVNSPMNKGDTEVM

Sheep

Polyclonal

IgG

Protein G affinity chromatography.

5 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Sheep anti Human Chromogranin antibodyrecognizes human chromogranin A, a secreted peptide that inhibits glucose-induced insulin release. Chromogranin A is an activator of microglia (Taupenaut et al. 1996) and is notably upregulated and prominantly expressed in the senile plaques associated with Alzheimer's disease (Yasuhara et al. 1994).

CgA, CHGA, Chromogranin-A, Pituitary secretory protein I, SP-I