Recombinant Anti-CDX2 Antibody [rCDX2/6921] - BSA and Azide free (A278467)

Anti-CDX2 Antibody [rCDX2/6921] - BSA and Azide free

Recombinant mouse monoclonal [rCDX2/6921] antibody to CDX2.

The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

IHC-P: 1-2 µg/ml

Human

Recombinant fragments corresponding to human CDX2 protein. The exact sequences are proprietary.

Mouse

Monoclonal

rCDX2/6921

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

40 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CDX2 Antibody [rCDX2/6921] (A277879).

Caudal-type homeobox protein 2, CDX-3, CDX3, Homeobox protein CDX-2