Recombinant Anti-CDX2 Antibody [rCDX2/1690] (A248114)

Anti-CDX2 Antibody [rCDX2/1690]

Recombinant mouse monoclonal [rCDX2/1690] antibody to CDX2.

The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

ELISA, IHC-P

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 150-249, of human CDX2 protein. The exact sequence is proprietary.

Mouse

Monoclonal

rCDX2/1690

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

40 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CDX2 Antibody [rCDX2/1690] - BSA and Azide free (A251297).

Caudal-type homeobox protein 2, CDX-3, CDX3, Homeobox protein CDX-2