Anti-CD99 Antibody [MIC2/877] - BSA and Azide free (A252510)

Anti-CD99 Antibody [MIC2/877] - BSA and Azide free

Mouse monoclonal [MIC2/877] antibody to CD99.

This antibody recognizes a sialoglycoprotein of 27-32kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewings sarcoma cells and primitive peripheral neuroectodermal tumors.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

This antibody does not cross react with Rat.

Recombinant full-length human MIC2 protein.

Mouse

Monoclonal

MIC2/877

IgG1

Protein A/G chromatography.

1 mg/ml

27-32 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD99 Antibody [MIC2/877] (A249330).

12E7, CD99 antigen, E2 antigen, MIC2, MIC2X, MIC2Y, Protein MIC2, T-cell surface glycoprotein E2