Anti-CD8B Antibody [H35-17.2] (A251034)

Anti-CD8B Antibody [H35-17.2]

Rat monoclonal [H35-17.2] antibody to CD8B.

This antibody reacts with the Mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.

Functional Studies, Flow Cytometry, IF

Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml

Mouse

This antibody does not cross react with Human.

Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c.

Rat

Monoclonal

H35-17.2

IgG2b

kappa

Protein A/G chromatography.

200 µg/ml

37 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD8B Antibody [H35-17.2] - BSA and Azide free (A254213).

CD8B1, T-cell surface glycoprotein CD8 beta chain