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Anti-CD80 Antibody [C80/3544] (A250640)

Mouse monoclonal [C80/3544] antibody to CD80 for ELISA and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-CD80 Antibody [C80/3544]
Description
Mouse monoclonal [C80/3544] antibody to CD80.
Specificity
T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
Applications
ELISA, IHC-P
Dilutions
IHC-P: 2-4 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 35-142, of human CD80 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
C80/3544
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
60 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD80 Antibody [C80/3544] - BSA and Azide free (A253820).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-CD80 Antibody [C80/3544] (A250640)? Please let us know so that we can list the citation on this page.

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