Anti-CD8 Antibody [4B11] (A279342)

Anti-CD8 Antibody [4B11]

Mouse monoclonal [4B11] antibody to CD8.

This antibody recognises the human CD8 cell surface antigen, a ~32 kDa glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. Mouse anti Human CD8 antibody, clone 4B11 was raised based on an earlier successful strategy used to generate rabbit polyclonal antibodies against human CD8 employing the same immunizing peptide. Mouse anti Human CD8 antibody, clone 4B11 has been reported as being suitable for use in Western blotting.

WB, IHC-P, IHC-Fr

IHC-Fr: 1:50, IHC-P: 1:50, WB: 1:25

Human

Synthetic peptide sequence C-KSDGKPSLSARYV derived from the C terminal region of the human CD8 alpha chain coupled to a N-terminal cysteine. The peptide was coupled to Bovine Serum Albumin and Keyhole Limpet Haemocyanin.

C-KSDGKPSLSARYV

Mouse

Monoclonal

4B11

IgG2b

Lot Specific

Tissue Culture Supernatant

Liquid

Supplied in 0.09% Sodium Azide.

Store undiluted at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD8 antibody, clone 4B11 recognizes the human CD8 cell surface antigen, a ~32 kDa glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. Mouse anti Human CD8 antibody, clone 4B11 was raised based on an earlier successful strategy used to generate rabbit polyclonal antibodies against human CD8 employing the same immunizing peptide (Mason et al. 1992).Mouse anti Human CD8 antibody, clone 4B11 has been reported as being suitable for use in Western blotting (Williamson et al. 1998) .

Activation B7-1 antigen, B7, BB1, CD28LG, CD28LG1, CD80, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80