Anti-CD8 alpha Antibody [YTS105.18] - BSA and Azide free (A282103)

$800

Rat monoclonal [YTS105.18] antibody to CD8 alpha for Flow Cytometry, IHC-Fr and IF.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 4-6 business days.
Name
Anti-CD8 alpha Antibody [YTS105.18] - BSA and Azide free
Description
Rat monoclonal [YTS105.18] antibody to CD8 alpha.
Specificity
This antibody recognises a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo, and induces transplantation tolerance in combination with CD4 antibodies (Cobbold et al. 1990 & Wise et al. 1998).
Applications
Flow Cytometry, IHC-Fr, IF
Dilutions
Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivity
Mouse
Immunogen
Mouse spleen cells.
Host
Rat
Clonality
Monoclonal
Clone ID
YTS105.18
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rat anti Mouse CD8, clone YTS105.18 recognizes a non polymorphic epitope on the mouse CD8 alpha chain. This antibody has been reported to block MHC I dependent T cell responses in vitro and in vivo, and induces transplantation tolerance in combination with CD4 antibodies (Cobbold et al. 1990 & Wise et al. 1998).
Synonyms
CD8a, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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