Anti-CD63 Antibody [LAMP3/7369] - BSA and Azide free (A316109)

Anti-CD63 Antibody [LAMP3/7369] - BSA and Azide free

Mouse monoclonal [LAMP3/7369] antibody to CD63.

CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

FUNC, IP, Flow Cytometry, IF, IHC-P

HL60, THP-1 or NIH/3T3 cells. Human spleen, melanoma or lymphoma.

Functional studies, IP: 1-2 µg per 100-500ug of total protein (1ml of cell lysate), Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 100-200) of human CD63 protein. The exact sequence is proprietary.

Mouse

Monoclonal

LAMP3/7369

kappa

Protein A/G chromatography.

1 mg/ml

26 kDa (core protein) / 30-60 kDa (glycosylated)

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD63 antigen, Granulophysin, LAMP-3, Limp1, Lysosomal-associated membrane protein 3, Lysosome integral membrane protein 1, Melanoma-associated antigen ME491, MLA1, OMA81H, TSPAN30