Anti-CD63 Antibody [LAMP3/4949] - BSA and Azide free (A278450)

Anti-CD63 Antibody [LAMP3/4949] - BSA and Azide free

Mouse monoclonal [LAMP3/4949] antibody to CD63.

CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Functional Studies, IP, Flow Cytometry, IF, IHC-P

IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Porcine

Recombinant full-length human CD63 protein.

Mouse

Monoclonal

LAMP3/4949

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

26 kDa (core protein) / 30-60 kDa (glycosylated)

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD63 Antibody [LAMP3/4949] (A277862).

CD63 antigen, Granulophysin, LAMP-3, Limp1, Lysosomal-associated membrane protein 3, Lysosome integral membrane protein 1, Melanoma-associated antigen ME491, MLA1, OMA81H, TSPAN30