Anti-CD62L Antibody [LAM1-116] (A249951)

Anti-CD62L Antibody [LAM1-116]

Mouse monoclonal [LAM1-116] antibody to CD62L.

Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

ELISA, Flow Cytometry, WB

Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml

Human

Supernatant from phorbol myristic acid activated human peripheral blood leukocytes.

Mouse

Monoclonal

LAM1-116

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

65-75 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD62L Antibody [LAM1-116] - BSA and Azide free (A253131).

CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHR, LYAM1, Lymph node homing receptor, SELL