Anti-CD52 Antibody [YTH66.9HL] (A282090)

Anti-CD52 Antibody [YTH66.9HL]

Rat monoclonal [YTH66.9HL] antibody to CD52.

This antibody recognises human CD52, also known as CAMPATH-1. The CD52 antigen is a small heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the antigen on SDS-PAGE is 25-29 kDa.CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.Humanized versions of CAMPATH-1 specific antibodies are used for the treatment of a range of lymphoid malignancies.

WB, IHC-Fr, Flow Cytometry, Cytotoxic Assays

Flow Cytometry: 1:20, IHC-Fr: 1:20, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Human, Cynomolgus monkey

Human T lymphocytes.

Rat

Monoclonal

YTH66.9HL

IgM

Ammonium sulphate precipiation of tissue culture supernatant.

2 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at 4°C.

Rat anti Human CD52 antibody, clone YTH66.9HL recognizes human CD52, also known as CAMPATH-1. The CD52 antigen is a small heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the antigen on SDS-PAGE is 25-29 kDa.CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.Humanized versions of CAMPATH-1 specific antibodies are used for the treatment of a range of lymphoid malignancies (Blatt et al. 2014).

Cambridge pathology 1 antigen, CAMPATH-1 antigen, CDW52, Epididymal secretory protein E5, He5, Human epididymis-specific protein 5