Recombinant rabbit monoclonal [CD48/8601R] antibody to CD48.
Specificity
Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
Applications
IHC-P
Positive Control
Raji cells. Human lymph node or tonsil.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 59-178) of human CD48 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
CD48/8601R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
45 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, CD48 antigen, Leukocyte antigen MEM-102, Signaling lymphocytic activation molecule 2, SLAM family member 2, SLAMF2, TCT.1