Recombinant Anti-CD47 Antibody [rCD47/6589] (A277939)

Anti-CD47 Antibody [rCD47/6589]

Recombinant mouse monoclonal [rCD47/6589] antibody to CD47.

This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

IHC-P: 1-2 µg/ml

Human

Recombinant full-length human CD47 protein.

Mouse

Monoclonal

rCD47/6589

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

~50 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD47 Antibody [rCD47/6589] - BSA and Azide free (A278527).

Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6