Anti-CD45 Antibody [OX-1] (A281367)

Anti-CD45 Antibody [OX-1]

Mouse monoclonal [OX-1] antibody to CD45.

This antibody recognises CD45, also known as the leucocyte common antigen (LCA). The leucocyte common antigen consists of a family of heavily glycosylated membrane glycoproteins of molecular weight 180 – 240kDa.Antibodies recognising a common epitope on all of these isoforms are termed CD45, whilst those recognising only individual isoforms are termed CD45RA, CD45RO etc. OX-1 reacts with all forms of CD45 expressed by all haematopoietic cells, except erythrocytes.CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.This product is routinely tested in flow cytometry on rat splenocytes

Flow Cytometry, IHC-Fr, IF

Flow Cytometry: 1:100, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Rat

Rat Thymocyte Membrane Glycoproteins.

Mouse

Monoclonal

OX-1

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Rat CD45 antibody, clone OX-1 recognizes CD45, also known as the leucocyte common antigen (LCA). The leucocyte common antigen consists of a family of heavily glycosylated membrane glycoproteins of molecular weight 180 – 240kDa.Antibodies recognising a common epitope on all of these isoforms are termed CD45, whilst those recognising only individual isoforms are termed CD45RA, CD45RO etc. OX-1 reacts with all forms of CD45 expressed by all haematopoietic cells, except erythrocytes.CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.This product is routinely tested in flow cytometry on rat splenocytes

L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200