Anti-CD44 Antibody [Bu52] (A279900)

Anti-CD44 Antibody [Bu52]

Mouse monoclonal [Bu52] antibody to CD44.

This antibody recognises the human CD44 cell surface antigen, a ~100 kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and of the breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. recognises an epitope that is common to all CD44 isoforms. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.

IHC-P, IP, Flow Cytometry, IHC-Fr

Flow Cytometry: 1:25 - 1:100, IHC-P: 1:100 - 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Mouse

Monoclonal

Bu52

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human CD44 antibody, clone Bu52 recognizes the human CD44 cell surface antigen, a ~100 kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and of the breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. Mouse anti Human CD44 antibody, clone Bu52 recognizes an epitope that is common to all CD44 isoforms. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.

CD44 antigen, CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, LHR, MDU2, MDU3, MIC4