This antibody recognizes a neuraminidase-sensitive extracellular epitope on CD43, a 95-135 kDa type I transmembrane glycoprotein (mucin-type) which is involved in lymphocyte activation. CD43 is expressed by platelets and at high levels on the surface of all leukocytes. It is negative on resting B lymphocytes and erythrocytes.
Applications
Flow Cytometry, IP, WB, IHC-P, Functional Studies
Dilutions
FUNC: This antibody activates T lymphocytes and also induces apoptosis in hemopoietic progenitor cells, Flow Cytometry: 1-5 µg/ml, IHC-P: Positive Control: spleen, thymus, tonsil: 10 µg/ml.
Reactivity
Human
Immunogen
Human T lymphocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
MEM-59
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein A chromatography.
Concentration
1 mg/ml
Predicted MW
95-135 kDa
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline, pH 7.4, without Sodium Azide (0.2 µm filter sterilized). Endotoxin level is less than 0.01 EU/µg of the protein.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-CD43 Antibody [MEM-59] - Low endotoxin, Azide free (A85602)? Please let us know so that we can list the citation on this page.
Alternative products to Anti-CD43 Antibody [MEM-59] - Low endotoxin, Azide free (A85602)