Anti-CD4 Antibody [CACT138A] (A279988)

Anti-CD4 Antibody [CACT138A]

Mouse monoclonal [CACT138A] antibody to CD4.

This antibody recognises bovine CD4. CD4 regulates T cell activation and acts as an accessory protein for MHC II and TCR interaction. It is a marker for bovine T helper cells. In cattle CD4+ T cells can also be found in mediastinal haemolymph nodes, lymph nodes and parafollicular lymphatic tissue. Cattle infected with viral diarrhea virus had depleted numbers of CD4+ cells.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Bovine, Bison, Water Buffalo, Sheep, Goat

Con A activated bovine lymphocytes.

Mouse

Monoclonal

CACT138A

IgG1

1 mg/ml

Liquid

Supplied in serum free tissue culture medium containing proprietary protein free supplement and 0.09% Sodium Azide.

Store at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Bovine CD4, clone CACT138A, recognizes bovine CD4. CD4 regulates T cell activation and acts as an accessory protein for MHC II and TCR interaction. It is a marker for bovine T helper cells. In cattle CD4+ T cells can also be found in mediastinal haemolymph nodes, lymph nodes and parafollicular lymphatic tissue (Galeotti et al. 1993). Cattle infected with viral diarrhea virus had depleted numbers of CD4+ cells (Endsley et al. 2002).

B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDw40, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, TNFRSF5, Tumor necrosis factor receptor superfamily member 5