Anti-CD4 Antibody [b38c6c7] (FITC) (A279768)

$590

Mouse monoclonal [b38c6c7] antibody to CD4 (FITC) for IF and Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 4-6 business days.
Name
Anti-CD4 Antibody [b38c6c7] (FITC)
Description
Mouse monoclonal [b38c6c7] antibody to CD4 (FITC).
Specificity
This antibody recognises a ~55 kDa porcine homologue of the human CD4 antigen found on the surface of T helper cells. Clone b38c6c7 was confirmed to bind to a member of the CD4 alpha cluster at the ‘Third International Workshop on Swine Leukocyte Differentiation Antigens’. Porcine CD4 is a type 1 transmembrane member of the immunoglobulin superfamily. Pigs are unusual among mammalian species as they appear to have four populations of resting T lymphocytes. In addition to CD4+/CD8- and CD4-/CD8+ lymphocytes they also appear to have significant populations of CD4-/CD8- and CD4+/CD8+ cells. Lymphoblasts with a double positive phenotype have been described in other species but not in the case of mature peripheral T cells.
Applications
IF, Flow Cytometry
Dilutions
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reactivity
Porcine
Immunogen
Porcine leukocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
b38c6c7
Isotype
IgG1
Conjugate

FITC

Excitation: 490nm, Emission: 525nm

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
100 µg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
General Notes
Mouse anti Porcine CD4, clone b38c6c7 recognizes a ~55 kDa porcine homologue of the human CD4 antigen found on the surface of T helper cells. Clone b38c6c7 was confirmed to bind to a member of the CD4 alpha cluster at the ‘Third International Workshop on Swine Leukocyte Differentiation Antigens’ (Haverson et al. 2001).Porcine CD4 is a type 1 transmembrane member of the immunoglobulin superfamily. Pigs are unusual among mammalian species as they appear to have four populations of resting T lymphocytes. In addition to CD4+/CD8- and CD4-/CD8+ lymphocytes they also appear to have significant populations of CD4-/CD8- and CD4+/CD8+ cells. Lymphoblasts with a double positive phenotype have been described in other species but not in the case of mature peripheral T cells (Saalmuller et al. 1987).
Synonyms
B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDw40, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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