Anti-CD38 Antibody [90] (PE) (A278765)

Anti-CD38 Antibody [90] (PE)

Rat monoclonal [90] antibody to CD38 (PE).

This antibody recognises the murine CD38 cell surface antigen, a ~42-46kDa glycoprotein expressed by B lymphocytes, a proportion of peripheral T lymphocytes and by peritoneal macrophages.In the mouse CD38 is expressed by follicular B cells, is down regulated on germinal centre B cells, and not expressed by mature plasma cells. This pattern of expression contrasts strikingly with that seen in the human.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl. The Fc region of monoclonal antibodies may bind to cells expressing low affinity fc receptors. This may be reduced by using SeroBlock FcR (BUF041A/BUF041B).

Mouse

Mouse pre-B cells derived from IL-7 dependent bone marrow cultures.

Rat

Monoclonal

90

Lot Specific

Liquid

Supplied in Phosphate Buffered Saline with Sucrose and <0.1% Sodium Azide.

Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Rat anti Mouse CD38 antibody, clone 90 recognizes the murine CD38 cell surface antigen, a ~42-46kDa glycoprotein expressed by B lymphocytes, a proportion of peripheral T lymphocytes and by peritoneal macrophages.In the mouse CD38 is expressed by follicular B cells, is down regulated on germinal centre B cells, and not expressed by mature plasma cells. This pattern of expression contrasts strikingly with that seen in the human.

2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADPRC 1, cADPR hydrolase 1, Cyclic ADP-ribose hydrolase 1, EC:2.4.99.20, T10

This product is for research use only. It is not intended for diagnostic or therapeutic use.