Anti-CD36 Antibody [CD36/7218] (A314690)

Anti-CD36 Antibody [CD36/7218]

Mouse monoclonal [CD36/7218] antibody to CD36.

Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.

Platelets, monocytes, macrophages, microvascular endothelial cells in a tonsil. Heart tissue lysate.

IHC: 1-2 µg/ml

Human

Recombinant full-length human CD36 protein.

Mouse

Monoclonal

CD36/7218

Protein A/G chromatography.

200 µg/ml

80-90 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

FAT, Fatty acid translocase, Glycoprotein IIIb, GP3B, GP4, GPIIIB, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet glycoprotein 4